מסגרת עם רקע לכותרת

Shared genetic risk factors across carbamazepine‐induced hypersensitivity reactions

תמונת נושא מאמר
15.05.2019 |

reactions (CBZHRs) including serious cutaneous adverse reactions (SCAR) and liver injury (CBZDILI).

In order to evaluate shared or phenotypespecific genetic predisposing factors for CBZHRs, we performed a metaanalysis of two GWAS studies on a total of 43 wellphenotyped Northern and Southern European CBZSCAR cases and 10,701 population controls and a GWAS on 12 CBZDILI cases and 8,438 ethnicallymatched population controls.

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